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Cannabis suppresses antitumor immunity by inhibiting JAK/STAT signaling in T cells through CNR2

Xiong, X., Chen, S., Shen, J. et al. Cannabis suppresses antitumor immunity by inhibiting JAK/STAT signaling in T cells through CNR2. Sig Transduct Target Ther7, 99 (2022). https://doi.org/10.1038/s41392-022-00918-y

Auts2 deletion involves in DG hypoplasia and social recognition deficit: The developmental and neural circuit mechanisms

JUN LI, XIAOXUAN SUN, YANG YOU, QIONGWEI LI, CHENGWEN WEI, LINNAN ZHAO, MENGWEN SUN, HU MENG, TIAN, ZHANG, WEIHUA YUE ,LIFANG WANG, AND DAI ZHANG, SCIENCE ADVANCES, 2 Mar 2022, Vol 8, Issue 9, DOI: 10.1126/sciadv.abk1238

Meiotic Cas9 expression mediates gene conversion in the male and female mouse germline

Weitzel, A. J., Grunwald, H.A., Weber, C. et al. Meiotic Cas9 Expression Mediates Gene Conversion in the Male and Female Mouse Germline. PLOS Biology. (2021). https://doi.org/10.1371/journal.pbio.3001478.

PINK1 kinase dysfunction triggers neurodegeneration in the primate brain without impacting mitochondrial homeostasis

Yang, W., Guo, X., Tu, Z. et al. PINK1 kinase dysfunction triggers neurodegeneration in the primate brain without impacting mitochondrial homeostasis. Protein Cell (2021). https://doi.org/10.1007/s13238-021-00888-x

Two novel human anti-CD25 antibodies with antitumor activity inversely related to their affinity and in vitro activity

Song, D., Liu, X., Dong, C. et al. Two novel human anti-CD25 antibodies with antitumor activity inversely related to their affinity and in vitro activity. Sci Rep 11, 22966 (2021). https://doi.org/10.1038/s41598-021-02449-y

BMI1 regulates multiple myeloma-associated macrophage’s pro-myeloma functions

Zhang, D., Huang, J., Wang, F. et al. BMI1 regulates multiple myeloma-associated macrophage’s pro-myeloma functions. Cell Death Dis 12, 495 (2021). https://doi.org/10.1038/s41419-021-03748-y

The combination of CUDC-907 and gilteritinib shows promising in vitro and in vivo antileukemic activity against FLT3-ITD AML

Qiao, X., Ma, J., Knight, T. et al. The combination of CUDC-907 and gilteritinib shows promising in vitro and in vivo antileukemic activity against FLT3-ITD AML. Blood Cancer J. 11, 111 (2021). https://doi.org/10.1038/s41408-021-00502-7

Targeting epidermal growth factor-overexpressing triple-negative breast cancer by natural killer cells expressing a specific chimeric antigen receptor

Liu, Y., Zhou, Y., Huang, K-H. et al. Targeting epidermal growth factor-overexpressing triple-negative breast cancer by natural killer cells expressing a specific chimeric antigen receptor. Cell Prolif. (2020). https://doi.org/10.1111/cpr.12858

Natural small molecule triptonide inhibits lethal acute myeloid leukemia with FLT3-ITD mutation by targeting Hedgehog/FLT3 signaling

Xu, Y., Wang, P., Li, M. et al. Natural small molecule triptonide inhibits lethal acute myeloid leukemia with FLT3-ITD mutation by targeting Hedgehog/FLT3 signaling. Biomed Pharmacother. (2021). https://doi.org/10.1016/j.biopha.2020.111054

MUC1-Tn-targeting chimeric antigen receptor-modified Vγ9Vδ2 T cells with enhanced antigen-specific anti-tumor activity

Zhai, X., You, F., Xiang, S. et al. MUC1-Tn-targeting chimeric antigen receptor-modified Vγ9Vδ2 T cells with enhanced antigen-specific anti-tumor activity. Am J Cancer Res. (2021). PMID: 33520361