Publications using Off-the-shelf Models

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Dose escalation PET imaging for safety and effective therapy dose optimization of a bispecific antibody

Wang, Y., Pan, D., Huang, C. et al. Dose escalation PET imaging for safety and effective therapy dose optimization of a bispecific antibody. MAbs. (2020). DOI: 10.1080/19420862.2020.1748322

Deficiency in the anti-apoptotic protein DJ-1 promotes intestinal epithelial cell apoptosis and aggravates inflammatory bowel disease via p53

Zhang, J., Xu, M., Zhou, W. et al. Deficiency in the anti-apoptotic protein DJ-1 promotes intestinal epithelial cell apoptosis and aggravates inflammatory bowel disease via p53. J Biol Chem. (2020). DOI: 10.1074/jbc.RA119.010143

Long non-coding RNA SOX2OT promotes the stemness phenotype of bladder cancer cells by modulating SOX2

Zhan, Y., Chen, Z., He, S. et al. Long non-coding RNA SOX2OT promotes the stemness phenotype of bladder cancer cells by modulating SOX2. Molecular Cancer. (2020). https://doi.org/10.1186/s12943-020-1143-7

Preliminary biological evaluation of 123I-labelled anti-CD30-LDM in CD30-positive lymphomas murine models

Gong, J., Guo, F., Cheng, W. et al. Preliminary biological evaluation of 123I-labelled anti-CD30-LDM in CD30-positive lymphomas murine models. Artif Cells Nanomed Biotechnol. (2020). https://doi.org/10.1080/21691401.2019.1709857

A Tumor-Targeted Replicating Oncolytic Adenovirus Ad-TD-nsIL12 as a Promising Therapeutic Agent for Human Esophageal Squamous Cell Carcinoma

Zhang, Z., Zhang, C., Miao, J. et al. A Tumor-Targeted Replicating Oncolytic Adenovirus Ad-TD-nsIL12 as a Promising Therapeutic Agent for Human Esophageal Squamous Cell Carcinoma. Cells. (2020). https://doi.org/10.3390/cells9112438

Long non-coding RNA CASC9 promotes tumor growth and metastasis via modulating FZD6/Wnt/β-catenin signaling pathway in bladder cancer

Zhan, Y., Zhang, L., Yu, S. et al. Long non-coding RNA CASC9 promotes tumor growth and metastasis via modulating FZD6/Wnt/β-catenin signaling pathway in bladder cancer. J Exp Clin Cancer Res. (2020). https://doi.org/10.1186/s13046-020-01624-9

Sequential treatment with aT19 cells generates memory CAR-T cells and prolongs the lifespan of Raji-B-NDG mice

Chen, R., Wang, M., Liu, Q. et al. Sequential treatment with aT19 cells generates memory CAR-T cells and prolongs the lifespan of Raji-B-NDG mice. Cancer Lett. (2020). https://doi.org/10.1016/j.canlet.2019.10.022

HDAC2 inhibits EMT-mediated cancer metastasis by downregulating the long noncoding RNA H19 in colorectal cancer

Hu, X.-T., Xing, W., Zhao, R.-S. et al. HDAC2 inhibits EMT-mediated cancer metastasis by downregulating the long noncoding RNA H19 in colorectal cancer. J Exp Clin Cancer Res. (2020). https://doi.org/10.1186/s13046-020-01783-9

Cancer-secreted exosomal miR-1468-5p promotes tumor immune escape via the immunosuppressive reprogramming of lymphatic vessels

Zhou, C., Wei, W., Ma, J. et al. Cancer-secreted exosomal miR-1468-5p promotes tumor immune escape via the immunosuppressive reprogramming of lymphatic vessels. Mol Ther. (2021). https://doi.org/10.1016/j.ymthe.2020.12.034

NEK2 induces autophagy-mediated bortezomib resistance by stabilizing Beclin-1 in multiple myeloma

Xia, J., He, Y., Meng, B. et al. NEK2 induces autophagy-mediated bortezomib resistance by stabilizing Beclin-1 in multiple myeloma. Mol Oncol. (2020). https://doi.org/10.1002/1878-0261.12641