B-p53 KO rats
May 20, 2019
Tp53tm1/Bcgen rats are a useful model for studying tumor formation, screening in vivo carcinogenicity, and examining the efficacy of therapeutic agents. The Tp53 KO rat model was developed using targeted TALEN technology in the Sprague-Dawley strain. This model possesses a 12 bp deletion and 2 bp insertion within Exon 2 of Tp53 on chromosome 10. […]
B-Rag2/IL2rg KO rats
May 20, 2019
The B-Rag2-IL2rg knockout rat was developed using targeted TALEN technology in the Sprague-Dawley strain, and this model possesses Rag2 and IL2rg gene deletion. This strain was maintained by mating homozygous males with homozygous females on a Sprague-Dawley genetic background.
