B-Apoa4 KO rats

May 21, 2019

The Apoa4 KO rat was developed using targeted TALEN technology in the Sprague-Dawley strain. This model possesses an 8 bp deletion within Exon 2 on chromosome 8 causing a protein frame shift. This strain was maintained by mating homozygous males with homozygous females on a Sprague-Dawley genetic background.

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B-hPD-L1 MC38 Plus

May 21, 2019

The mouse Pdl1 gene was replaced by human PD-L1 coding sequence in B-hPD-L1 MC38 cells. Human PD-L1 is highly expressed on the surface of B-hPD-L1 MC38 plus cells.

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