Basic Information
Common name
B-hPD-L1 MC38 ad
Catalog number
321852
Aliases
DPPIVA, PD-L1alpha, SIMP
Disease
Colon carcinoma
Organism
Mouse
Strain
C57BL/6
Tissue types
Colon
Tissue
Colon
Application
B-hPD-L1 MC38 ad cells have the capability to establish tumors in vivo and can be used for efficacy studies.
NCBI Gene ID
Description
The exogenous promoter and chimeric CDS composed of mouse signal peptide, human IgV region, mouse extracellular region except IgV domain, moue transmembrane region and mouse intracellular region of PD-L1 gene was inserted to replace the IgV domain of mouse Pdl1 gene. Human PD-L1 is highly expressed on the surface of B-hPD-L1 MC38 ad cells.
