Basic Information
Common name
B-hPD-L1/hB7-H3 MC38
Catalog number
321842
Aliases
CD274;CD276
Disease
Colon carcinoma
Organism
Mouse
Strain
C57BL/6
Tissue types
Colon
Tissue
Colon
Application
B-hPD-L1/hB7-H3 MC38 cells have the capability to establish tumors in B-hPD-1/hB7-H3 mice in vivo and can be used for efficacy studies.
NCBI Gene ID
Description
The human PD-L1 and chimeric CDS including human B7-H3 were inserted into counterpart gene sites separately, so that the mouse Pd-l1 and B7-h3 were not expressed anymore, human PD-L1 and B7-H3 protein were highly expressed on the surface of B-hPD-L1/hB7-H3 MC38 cells.
