Basic Information
Strain Name
SD-Ldlrtm1/Bcgen
Stock Number
210506
Common Name
B-Ldlr KO rats
Source/Investigator
Bcgen (Beijing Biocytogen Co., Ltd)
Related Genes
Ldlr (low density lipoprotein receptor)
Species
Sprague Dawley
Appearance
White
Genotypes
LdlrKO (mut/mut)
NCBI Gene ID
Description
Ldlr KO rats were developed using targeted TALEN technology in the Sprague-Dawley strain. This model possesses a 2 bp deletion within Exon 1 of Ldlr on chromosome 8. This strain was maintained by mating homozygous males with homozygous females on a Sprague-Dawley genetic background.