Basic Information
Strain Name
C57BL/6-Gfaptm1(icre)/Bcgen
Stock Number
110144
Common Name
B-Gfap-iCre mice
Source/Investigator
Biocytogen Jiangsu Co., Ltd
Related Genes
Gfap (glial fibrillary acidic protein)
NCBI Gene ID
Species
C57BL/6J
Appearance
Black
Genotype
Gfap iCre (wt/mut)
Development
An iCre-WPRE-pA cassette was placed at the 5’ end of the Gfap gene using C57BL/6 embryonic stem cells. Neo cassette flanked by frt sites was inserted at downstream of pA. This strain was maintained on a C57BL/6 genetic background.
Application
This Gfap-iCre model is an efficient tool to study various gene functions when crossed with mice with different loxP site-flanked genes of interest, especially in studies of astrocytes cells related signaling.
