AACR 2022: Identifying New Therapeutic Antibodies Using Knockout Mice Expressing Human Immunoglobulin Variable Domain Genes
Conclusions
In conclusion, the RenMice™ HiTS (Hyperimmune Target Specific) Platform enables accelerated identification of fully human antibodies with increased diversity of antibody paratopes and species cross-reactivity. The RenMice™ HiTS Program is focusing on identifying more first-in-class drug targets.
