Basic Information
Strain Name
NOD.CB17-PrkdcscidIl2rgtm1Csf1tm1(CSF1)Thpotm1(THPO)/Bcgen
Common Name
B-NDG hCSF1/hTHPO mice
Background
B-NDG
Catalog number
120609
Related Genes
CSF1 (MCSF),THPO (thrombopoietin)
Description
Biocytogen independently developed the highly immunodeficient B-NDG hCSF1/hTHPO mice in which we replaced the gene encoding murine Csf1/Thpo by its human CDS region. This mouse combines a B-NDG mouse background and expresses human hCSF1/hTHPO protein, which will become a suitable animal model to investigate the development and function of human macrophages without irradiation treatment.
