Basic Information
Common name
B-hGUCY2C MC38
Catalog number
321837
Aliases
DIAR6, GC-C, GUC2C, MECIL, MUCIL, STAR
Disease
Colon carcinoma
Organism
Mouse
Strain
C57BL/6
Tissue types
Colon
Tissue
Colon
Application
B-hGUCY2C MC38 cells have the capability to establish tumors in C57BL/6 mice in vivo and can be used for efficacy studies.
NCBI Gene ID
Description
The chimeric CDS consist of human GUCY2C extracellular plus mouse Gucy2c intracellular region sequences was inserted to mouse Gucy2c gene exon 1 in B-hGUCY2C MC38 cells, so that the mouse GUCY2C was not expressed anymore, human GUCY2C was highly expressed on the surface of B-hGUCY2C MC38 cells.
