Basic Information
Common Name
B-hPD-L1 low MC38 plus
Catalog number
321853
Aliases
B7-H, B7H1, PD-L1, PDCD1L1, PDCD1LG1, PDL1, hPD-L1
Disease
Colon carcinoma
Organism
Mus musculus, mouse
Strain
C57BL/6
Tissue types
Colon
Tissue
Colon
Application
B-hPD-L1 low MC38 plus cells have the capability to establish tumors in vivo and can be used for efficacy studies.
NCBI Gene ID
Description
The chimeric CDS composed of mouse signal peptide, human IgV region, mouse extracellular region except IgV domain, moue transmembrane region and mouse intracellular region of PD-L1 gene was inserted to replace the IgV domain of mouse Pdl1 gene. Human PD-L1 is highly expressed on the surface of B-hPD-L1 low MC38 plus cells.
