Basic Information
Strain Name
C57BL/6-Tgfb1 tm1 /Bcgen
Stock Number
110164
Common Name
B-Tgfb1 cKO mice
Source/Investigator
Bcgen (Beijing Biocytogen Co., Ltd)
Related Genes
Tgfb1; TGF-Beta1 (transforming growth factor, beta 1)
Species
C57BL/6J
Appearance
Black
Genotypes
Tgfb1 CKO (mut/mut)
Development
A designed targeting vector containing 5’-homologous arm, loxP-Exon2- frt-Neo-frt-loxP, 3’-homologous arm, and DTA selection marker was introduced into C57BL/6 ES cells, replacing corresponding Tgfb1 exon 2 locus. The resulting chimeric animals were crossed to C57BL/6 mice to establish the colony.
NCBI Gene ID
